{"id":28,"date":"2023-03-07T18:27:24","date_gmt":"2023-03-07T17:27:24","guid":{"rendered":"https:\/\/mu-imagine.com\/?page_id=28"},"modified":"2024-06-21T16:34:53","modified_gmt":"2024-06-21T14:34:53","slug":"adaptive-optics-module-micao","status":"publish","type":"page","link":"https:\/\/mu-imagine.com\/ao-solutions\/adaptive-optics-module-micao\/","title":{"rendered":"MicAO"},"content":{"rendered":"

[et_pb_section fb_built=”1″ disabled_on=”off|off|off” _builder_version=”4.23.1″ _module_preset=”default” background_enable_color=”off” background_image=”https:\/\/mu-imagine.com\/wp-content\/uploads\/2024\/04\/Micao-background.png” bottom_divider_style=”wave” bottom_divider_color=”#cbe9fb” bottom_divider_height=”70px” global_colors_info=”{}”][et_pb_row column_structure=”3_5,1_5,1_5″ make_equal=”on” _builder_version=”4.23.1″ _module_preset=”default” max_width=”1400px” custom_css_main_element=”align-items: center;” global_colors_info=”{}”][et_pb_column type=”3_5″ _builder_version=”4.23.1″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.23.1″ _module_preset=”default” text_font=”Montserrat||||||||” text_text_color=”#FFFFFF” text_font_size=”13px” header_font=”Montserrat|700|||||||” header_text_color=”#cbe9fb” header_font_size=”33px” custom_margin=”||0px||false|false” locked=”off” global_colors_info=”{}”]<\/p>\n

MicAO, an adaptive optics module<\/span>
for super resolution microscopy<\/h1>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_5″ _builder_version=”4.23.1″ _module_preset=”default” global_colors_info=”{}”][et_pb_button button_url=”https:\/\/www.imagine-optic.com\/products\/micao-3dsr-adaptive-optics-system\/” url_new_window=”on” button_text=”Request a prequote” disabled_on=”on|on|on” _builder_version=”4.23.1″ _module_preset=”default” custom_button=”on” button_text_size=”16px” button_text_color=”#000000″ button_bg_color=”#cbe9fb” button_border_width=”0px” button_border_color=”#C5F5FF” button_border_radius=”100px” button_font=”Montserrat|600|||||||” button_icon=”h||divi||400″ disabled=”on” locked=”off” global_colors_info=”{}”][\/et_pb_button][\/et_pb_column][et_pb_column type=”1_5″ _builder_version=”4.23.1″ _module_preset=”default” global_colors_info=”{}”][et_pb_button button_url=”https:\/\/mu-imagine.com\/wp-content\/uploads\/2024\/03\/MicAO-adaptive-optics-module-datasheet.pdf” url_new_window=”on” button_text=”Download Datasheet” _builder_version=”4.23.1″ _module_preset=”default” custom_button=”on” button_text_size=”16px” button_text_color=”#000000″ button_bg_color=”#cbe9fb” button_border_width=”0px” button_border_color=”#C5F5FF” button_border_radius=”100px” button_font=”Montserrat|600|||||||” button_icon=”||divi||400″ locked=”off” global_colors_info=”{}”][\/et_pb_button][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_2,1_6,1_6,1_6″ make_equal=”on” _builder_version=”4.23.1″ _module_preset=”default” max_width=”1400px” custom_css_main_element=”align-items: flex-end;” global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”4.23.1″ _module_preset=”default” global_colors_info=”{}”][et_pb_image src=”https:\/\/mu-imagine.com\/wp-content\/uploads\/2024\/04\/Module_MicAO.png” alt=”Image of MicAO, adaptive optics module” title_text=”micao_ao-module” _builder_version=”4.23.1″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][et_pb_column type=”1_6″ _builder_version=”4.23.1″ _module_preset=”default” global_colors_info=”{}”][et_pb_blurb title=”Increase resolution” image=”https:\/\/mu-imagine.com\/wp-content\/uploads\/2024\/04\/Resolution_micao.png” alt=”Resolution improvement icon” image_icon_width=”130px” content_max_width=”100%” module_class=”header-icons” _builder_version=”4.23.1″ _module_preset=”default” header_level=”h3″ header_font=”Montserrat|600|||||||” header_text_align=”center” header_text_color=”#FFFFFF” header_font_size=”16px” body_font=”Montserrat||||||||” body_text_align=”center” body_text_color=”#FFFFFF” body_font_size=”13px” body_line_height=”1em” image_icon_custom_margin=”||5px||false|false” width=”100%” animation=”off” locked=”off” global_colors_info=”{}”]<\/p>\n

by correcting aberrations<\/p>\n

[\/et_pb_blurb][\/et_pb_column][et_pb_column type=”1_6″ _builder_version=”4.23.1″ _module_preset=”default” global_colors_info=”{}”][et_pb_blurb title=”Shape your PSF” image=”https:\/\/mu-imagine.com\/wp-content\/uploads\/2024\/04\/PSF_micao.png” alt=”3D localization icon” image_icon_width=”115px” content_max_width=”100%” module_class=”header-icons” _builder_version=”4.23.1″ _module_preset=”default” header_level=”h3″ header_font=”Montserrat|600|||||||” header_text_align=”center” header_text_color=”#FFFFFF” header_font_size=”16px” body_font=”Montserrat||||||||” body_text_align=”center” body_text_color=”#FFFFFF” body_font_size=”13px” body_line_height=”1em” image_icon_custom_margin=”||5px||false|false” width=”100%” animation=”off” locked=”off” global_colors_info=”{}”]<\/p>\n

and go 3D<\/p>\n

[\/et_pb_blurb][\/et_pb_column][et_pb_column type=”1_6″ _builder_version=”4.23.1″ _module_preset=”default” global_colors_info=”{}”][et_pb_blurb title=”Image deeper” image=”https:\/\/mu-imagine.com\/wp-content\/uploads\/2024\/04\/Deep_micao.png” alt=”In depth imaging icon” image_icon_width=”102px” content_max_width=”100%” module_class=”header-icons” _builder_version=”4.23.1″ _module_preset=”default” header_level=”h3″ header_font=”Montserrat|600|||||||” header_text_align=”center” header_text_color=”#FFFFFF” header_font_size=”16px” body_font=”Montserrat||||||||” body_text_align=”center” body_text_color=”#FFFFFF” body_font_size=”13px” body_line_height=”1em” image_icon_custom_margin=”||5px||false|false” width=”100%” custom_margin=”0px||||false|false” custom_margin_tablet=”0px||||false|false” custom_margin_phone=”38px||||false|false” custom_margin_last_edited=”on|phone” custom_padding=”0px||||false|false” animation=”off” locked=”off” global_colors_info=”{}”]<\/p>\n

up to 50\u00b5m depth<\/p>\n

[\/et_pb_blurb][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ disabled_on=”off|off|off” _builder_version=”4.23.1″ _module_preset=”default” background_color=”#cbe9fb” background_enable_image=”off” background_pattern_repeat_origin=”center” global_colors_info=”{}”][et_pb_row _builder_version=”4.23.1″ _module_preset=”default” max_width=”1400px” custom_padding=”0px|||||” locked=”off” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.23.1″ _module_preset=”default” global_colors_info=”{}”][et_pb_heading title=”Description” _builder_version=”4.23.1″ _module_preset=”default” title_level=”h2″ title_font=”Montserrat|700|||||||” title_text_color=”#000000″ title_font_size=”25px” custom_margin=”||-15px||false|false” custom_margin_tablet=”||-30px||false|false” custom_margin_phone=”||-30px||false|false” custom_margin_last_edited=”on|phone” global_colors_info=”{}”][\/et_pb_heading][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_2,1_2″ use_custom_gutter=”on” gutter_width=”2″ make_equal=”on” _builder_version=”4.23.1″ _module_preset=”default” max_width=”1400px” custom_css_main_element=”display: flex;||align-items: center;” global_colors_info=”{}” custom_css_main_element_last_edited=”on|phone” custom_css_main_element_phone=”display: block;” custom_css_main_element_tablet=”display: block;”][et_pb_column type=”1_2″ _builder_version=”4.20.1″ _module_preset=”default” global_colors_info=”{}”][et_pb_video src=”https:\/\/www.youtube.com\/watch?v=4sl-XvhGnUQ&ab_channel=ImagineOptic” image_src=”\/\/i.ytimg.com\/vi\/4sl-XvhGnUQ\/hqdefault.jpg” play_icon_color=”#50D3E1″ use_icon_font_size=”on” icon_font_size=”70px” _builder_version=”4.23.1″ _module_preset=”default” max_width=”80%” max_width_tablet=”80%” max_width_phone=”80%” max_width_last_edited=”on|desktop” box_shadow_style=”preset1″ locked=”off” global_colors_info=”{}”][\/et_pb_video][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.20.1″ _module_preset=”default” custom_css_main_element=”margin: auto;” global_colors_info=”{}”][et_pb_text _builder_version=”4.23.1″ _module_preset=”default” text_font=”Montserrat||||||||” text_text_color=”#000000″ text_font_size=”13px” header_3_font=”Montserrat|700|||||||” header_3_text_color=”#FFFFFF” header_3_font_size=”25px” custom_margin=”||35px||false|false” header_3_font_size_tablet=”25px” header_3_font_size_phone=”22px” header_3_font_size_last_edited=”on|phone” global_colors_info=”{}”]<\/p>\n

MicAO Adaptive Optics (AO) device is the first AO add-on module<\/span> dedicated to techniques such as PhotoActivation Localization Microscopy (PALM<\/span>), Stochastic Optical Reconstruction Microscopy (STORM<\/span>) and Single Particle Tracking (SPT<\/span>).<\/p>\n

This module will enable you to get a better resolution<\/span> in both 2D&3D<\/span> for Single Molecule Localization Microscopy (SMLM<\/span>).<\/p>\n

[\/et_pb_text][et_pb_button button_url=”#” button_text=”Learn more about AO” disabled_on=”on|on|on” _builder_version=”4.23.1″ _module_preset=”default” custom_button=”on” button_text_size=”16px” button_text_color=”#000000″ button_bg_color=”#0cb8dc” button_border_width=”0px” button_border_color=”#50D3E1″ button_border_radius=”100px” button_font=”Montserrat|600|||||||” button_icon=”$||divi||400″ disabled=”on” global_colors_info=”{}”][\/et_pb_button][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ disabled_on=”off|off|off” _builder_version=”4.23.1″ _module_preset=”default” background_color=”#cbe9fb” global_colors_info=”{}”][et_pb_row _builder_version=”4.23.1″ _module_preset=”default” max_width=”1400px” custom_padding=”0px|||||” locked=”off” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.23.1″ _module_preset=”default” global_colors_info=”{}”][et_pb_heading title=”Technology & features” _builder_version=”4.23.1″ _module_preset=”default” title_level=”h2″ title_font=”Montserrat|700|||||||” title_text_color=”#000000″ title_font_size=”25px” custom_margin=”||-70px||false|false” custom_margin_tablet=”||-7px||false|false” custom_margin_phone=”||-7px||false|false” custom_margin_last_edited=”on|phone” locked=”off” global_colors_info=”{}”][\/et_pb_heading][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_2,1_2″ make_equal=”on” _builder_version=”4.23.1″ _module_preset=”default” max_width=”1400px” custom_margin=”||50px||false|false” custom_padding=”0px||0px||false|false” custom_css_main_element=”align-items: center;” global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”4.23.1″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.23.1″ _module_preset=”default” text_font=”Montserrat|700|||||||” text_text_color=”#02486A” text_font_size=”16px” header_3_font=”Open Sans|700|||||||” header_3_text_color=”#000000″ header_3_font_size=”25px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#1b375c” header_4_font_size=”20px” custom_margin=”0px||16px||false|false” header_3_font_size_tablet=”25px” header_3_font_size_phone=”22px” header_3_font_size_last_edited=”on|phone” locked=”off” global_colors_info=”{}”]<\/p>\n

How is it implemented ?<\/h4>\n

[\/et_pb_text][et_pb_blurb use_icon=”on” font_icon=”R||divi||400″ icon_color=”#02486A” icon_placement=”left” image_icon_width=”22px” content_max_width=”100%” _builder_version=”4.23.1″ _module_preset=”default” body_font=”Montserrat||||||||” body_text_color=”#000000″ body_font_size=”13px” body_line_height=”1.3em” custom_margin=”||10px||false|false” animation=”off” locked=”off” global_colors_info=”{}”]<\/p>\n

Added between the side port of your inverted frame microscope and the imaging camera<\/p>\n

[\/et_pb_blurb][et_pb_blurb use_icon=”on” font_icon=”R||divi||400″ icon_color=”#02486A” icon_placement=”left” image_icon_width=”22px” content_max_width=”100%” _builder_version=”4.23.1″ _module_preset=”default” body_font=”Montserrat||||||||” body_text_color=”#000000″ body_font_size=”13px” body_line_height=”1.3em” custom_margin=”||10px||false|false” animation=”off” locked=”off” global_colors_info=”{}”]<\/p>\n

Functions as an image relay : allows you to add other modules (dual color view device, microscope port splitters…)<\/p>\n

[\/et_pb_blurb][et_pb_blurb use_icon=”on” font_icon=”R||divi||400″ icon_color=”#02486A” icon_placement=”left” image_icon_width=”22px” content_max_width=”100%” _builder_version=”4.23.1″ _module_preset=”default” body_font=”Montserrat||||||||” body_text_color=”#000000″ body_font_size=”13px” body_line_height=”1.3em” custom_margin=”||10px||false|false” animation=”off” locked=”off” global_colors_info=”{}”]<\/p>\n

Compatible with 60x and 100x objective lenses<\/p>\n

[\/et_pb_blurb][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.23.1″ _module_preset=”default” global_colors_info=”{}”][et_pb_image src=”https:\/\/mu-imagine.com\/wp-content\/uploads\/2024\/04\/Module-with-microscope_MicAO.png” alt=”MicAO adaptive optics module inserted in inverted microscope side port” title_text=”micao-microscope_ao-module” align=”center” _builder_version=”4.23.1″ _module_preset=”default” max_width=”75%” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_2,1_2″ make_equal=”on” _builder_version=”4.23.1″ _module_preset=”default” max_width=”1400px” custom_margin=”||50px||false|false” custom_padding=”0px||0px||false|false” custom_css_main_element=”align-items: center;” global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”4.23.1″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.23.1″ _module_preset=”default” text_font=”Montserrat|700|||||||” text_text_color=”#02486A” text_font_size=”16px” header_3_font=”Open Sans|700|||||||” header_3_text_color=”#000000″ header_3_font_size=”25px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#1b375c” header_4_font_size=”20px” custom_margin=”0px||16px||false|false” header_3_font_size_tablet=”25px” header_3_font_size_phone=”22px” header_3_font_size_last_edited=”on|phone” locked=”off” global_colors_info=”{}”]<\/p>\n

Advantages of MicAO<\/h4>\n

[\/et_pb_text][et_pb_blurb use_icon=”on” font_icon=”R||divi||400″ icon_color=”#02486A” icon_placement=”left” image_icon_width=”22px” content_max_width=”100%” _builder_version=”4.23.1″ _module_preset=”default” body_font=”Montserrat||||||||” body_text_color=”#000000″ body_font_size=”13px” body_line_height=”1.3em” custom_margin=”||10px||false|false” animation=”off” locked=”off” global_colors_info=”{}”]<\/p>\n

Restores Point Spread Function (PSF) symmetry<\/p>\n

[\/et_pb_blurb][et_pb_blurb use_icon=”on” font_icon=”R||divi||400″ icon_color=”#02486A” icon_placement=”left” image_icon_width=”22px” content_max_width=”100%” _builder_version=”4.23.1″ _module_preset=”default” body_font=”Montserrat||||||||” body_text_color=”#000000″ body_font_size=”13px” body_line_height=”1.3em” custom_margin=”||10px||false|false” animation=”off” locked=”off” global_colors_info=”{}”]<\/p>\n

Doubles the number of detected photons<\/p>\n

[\/et_pb_blurb][et_pb_blurb use_icon=”on” font_icon=”R||divi||400″ icon_color=”#02486A” icon_placement=”left” image_icon_width=”22px” content_max_width=”100%” _builder_version=”4.23.1″ _module_preset=”default” body_font=”Montserrat||||||||” body_text_color=”#000000″ body_font_size=”13px” body_line_height=”1.3em” custom_margin=”||10px||false|false” animation=”off” locked=”off” global_colors_info=”{}”]<\/p>\n

Improves near diffraction-limited resolution<\/p>\n

[\/et_pb_blurb][et_pb_blurb use_icon=”on” font_icon=”R||divi||400″ icon_color=”#02486A” icon_placement=”left” image_icon_width=”22px” content_max_width=”100%” _builder_version=”4.23.1″ _module_preset=”default” body_font=”Montserrat||||||||” body_text_color=”#000000″ body_font_size=”13px” body_line_height=”1.3em” custom_margin=”||10px||false|false” animation=”off” locked=”off” global_colors_info=”{}”]<\/p>\n

Allows you to create a perfect PSF ecoding astigmatism or tetrapod to go 3D<\/p>\n

[\/et_pb_blurb][et_pb_blurb use_icon=”on” font_icon=”R||divi||400″ icon_color=”#02486A” icon_placement=”left” image_icon_width=”22px” content_max_width=”100%” _builder_version=”4.23.1″ _module_preset=”default” body_font=”Montserrat||||||||” body_text_color=”#000000″ body_font_size=”13px” body_line_height=”1.3em” custom_margin=”||10px||false|false” animation=”off” locked=”off” global_colors_info=”{}”]<\/p>\n

Gives you a better 2D and 3D localization precision<\/p>\n

[\/et_pb_blurb][et_pb_blurb use_icon=”on” font_icon=”R||divi||400″ icon_color=”#02486A” icon_placement=”left” image_icon_width=”22px” content_max_width=”100%” _builder_version=”4.23.1″ _module_preset=”default” body_font=”Montserrat||||||||” body_text_color=”#000000″ body_font_size=”13px” body_line_height=”1.3em” custom_margin=”||0px||false|false” animation=”off” locked=”off” global_colors_info=”{}”]<\/p>\n

Is compatible with long-term imaging<\/p>\n

[\/et_pb_blurb][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.23.1″ _module_preset=”default” global_colors_info=”{}”][et_pb_image src=”https:\/\/mu-imagine.com\/wp-content\/uploads\/2024\/04\/PSF_MicAO-1.png” alt=”PSF before and after correction with MicAO” title_text=”psf_ao-module” align=”center” _builder_version=”4.23.1″ _module_preset=”default” max_width=”75%” max_height=”1000px” custom_padding=”0px||||false|false” box_shadow_style=”preset1″ global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_2,1_2″ make_equal=”on” _builder_version=”4.23.1″ _module_preset=”default” max_width=”1400px” custom_margin=”||0px||false|false” custom_padding=”0px||0px||false|false” custom_css_main_element=”align-items: center;” global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”4.23.1″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.23.1″ _module_preset=”default” text_font=”Montserrat|700|||||||” text_text_color=”#02486A” text_font_size=”16px” header_3_font=”Open Sans|700|||||||” header_3_text_color=”#000000″ header_3_font_size=”25px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#1b375c” header_4_font_size=”20px” custom_margin=”0px||16px||false|false” header_3_font_size_tablet=”25px” header_3_font_size_phone=”22px” header_3_font_size_last_edited=”on|phone” locked=”off” global_colors_info=”{}”]<\/p>\n

How does it work ?<\/h4>\n

[\/et_pb_text][et_pb_blurb use_icon=”on” font_icon=”R||divi||400″ icon_color=”#02486A” icon_placement=”left” image_icon_width=”22px” content_max_width=”100%” _builder_version=”4.23.1″ _module_preset=”default” body_font=”Montserrat||||||||” body_text_color=”#000000″ body_font_size=”13px” body_line_height=”1.3em” custom_margin=”||10px||false|false” animation=”off” locked=”off” global_colors_info=”{}”]<\/p>\n

Enables you to function in open-loop configuration<\/p>\n

[\/et_pb_blurb][et_pb_blurb use_icon=”on” font_icon=”R||divi||400″ icon_color=”#02486A” icon_placement=”left” image_icon_width=”22px” content_max_width=”100%” _builder_version=”4.23.1″ _module_preset=”default” body_font=”Montserrat||||||||” body_text_color=”#000000″ body_font_size=”13px” body_line_height=”1.3em” custom_margin=”||10px||false|false” animation=”off” locked=”off” global_colors_info=”{}”]<\/p>\n

Helps you to apply 3N alogorithm to detect and correct aberrations, thanks to MicAO software<\/p>\n

[\/et_pb_blurb][et_pb_blurb use_icon=”on” font_icon=”R||divi||400″ icon_color=”#02486A” icon_placement=”left” image_icon_width=”22px” content_max_width=”100%” _builder_version=”4.23.1″ _module_preset=”default” body_font=”Montserrat||||||||” body_text_color=”#000000″ body_font_size=”13px” body_line_height=”1.3em” custom_margin=”||10px||false|false” animation=”off” locked=”off” global_colors_info=”{}”]<\/p>\n

Allows you to control your mirror and shape your PSF<\/p>\n

[\/et_pb_blurb][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.23.1″ _module_preset=”default” global_colors_info=”{}”][et_pb_image src=”https:\/\/mu-imagine.com\/wp-content\/uploads\/2024\/04\/3D-PSF_MicAO.png” alt=”3D PSF” title_text=”3d-psf_ao-module” align=”center” _builder_version=”4.23.1″ _module_preset=”default” max_width=”75%” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ disabled_on=”off|off|off” _builder_version=”4.23.1″ _module_preset=”default” background_color=”#cbe9fb” global_colors_info=”{}”][et_pb_row use_custom_gutter=”on” gutter_width=”2″ _builder_version=”4.20.1″ _module_preset=”default” max_width=”1400px” custom_padding=”0px||0px||true|false” custom_css_main_element=”display: flex;” global_colors_info=”{}” custom_css_main_element_tablet=”display: flex;” custom_css_main_element_phone=”display: block;” custom_css_main_element_last_edited=”on|phone”][et_pb_column type=”4_4″ _builder_version=”4.20.1″ _module_preset=”default” global_colors_info=”{}”][et_pb_heading title=”Gallery” _builder_version=”4.23.1″ _module_preset=”default” title_level=”h2″ title_font=”Montserrat|700|||||||” title_text_color=”#000000″ title_font_size=”25px” custom_margin=”||30px||false|false” locked=”off” global_colors_info=”{}”][\/et_pb_heading][dipi_image_accordion accordion_height=”310px” active_image_relative_width=”2″ accordion_direction_tablet=”” accordion_direction_phone=”vertical” accordion_direction_last_edited=”on|phone” _builder_version=”4.23.1″ _module_preset=”default” custom_margin=”||0px||false|false” hover_enabled=”0″ global_colors_info=”{}” box_shadow_style=”preset3″ sticky_enabled=”0″][dipi_image_accordion_child bg_img=”https:\/\/mu-imagine.com\/wp-content\/uploads\/2024\/04\/PSF-through-time_MicAO.png” accordion_description=”Example images of the diffraction-limited fluorescent bead at different ambient temperatures without stabilization module inside MicAO.” _builder_version=”4.23.1″ _module_preset=”default” accordion_desc_font=”Montserrat|600|||||||” custom_padding=”|20px||20px|false|true” global_colors_info=”{}”][\/dipi_image_accordion_child][dipi_image_accordion_child bg_img=”https:\/\/mu-imagine.com\/wp-content\/uploads\/2024\/04\/Proteins_MicAO.png” accordion_description=”Combined two-color 3 dimensional PALM and dSTORM imaging of mEos2-Centrin1 (orange) and Alexa 647 labeled Cep164 (light blue). Vizualisation using VISP sofware (El Beheiry and Dahan, 2013). Courtesy of J. Sillibourne & I. Izeddin” _builder_version=”4.23.1″ _module_preset=”default” accordion_desc_font=”Montserrat|600|||||||” custom_padding=”|20px||20px|false|true” global_colors_info=”{}”][\/dipi_image_accordion_child][dipi_image_accordion_child bg_img=”https:\/\/mu-imagine.com\/wp-content\/uploads\/2024\/04\/VS-cylindrical-lens_MicAO.png” accordion_description=”Comparison of astigmatism induced by cylindrical lens (left) and deformable mirror (right). We can see increased localization number with the DM, a component of MicAO.” _builder_version=”4.23.1″ _module_preset=”default” accordion_desc_font=”Montserrat|600|||||||” custom_padding=”|20px||20px|false|true” global_colors_info=”{}”][\/dipi_image_accordion_child][\/dipi_image_accordion][et_pb_text _builder_version=”4.23.1″ _module_preset=”default” text_font=”Montserrat||||||||” text_text_color=”#DDE4E6″ text_font_size=”16px” header_3_font=”Montserrat|700|||||||” header_3_text_color=”#50D3E1″ header_3_font_size=”25px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#1b375c” header_4_font_size=”20px” custom_margin=”0px||35px||false|false” custom_padding=”8px||||false|false” header_3_font_size_tablet=”25px” header_3_font_size_phone=”22px” header_3_font_size_last_edited=”on|phone” header_4_font_size_tablet=”18px” header_4_font_size_phone=”18px” header_4_font_size_last_edited=”off|desktop” global_colors_info=”{}”]<\/p>\n

Selected publications<\/h4>\n

Ignacio Izeddin, Mohamed El Beheiry, Jordi Andilla, Daniel Ciepielewski, Xavier Darzacq, and Maxime Dahan, “PSF shaping using adaptive optics for three-dimensional single-molecule super-resolution imaging and tracking,” Opt. Express 20, 4957-4967 (2012)<\/a><\/p>\n

Glushonkov, O., R\u00e9al, E., Boutant, E. et al. Optimized protocol for combined PALM-dSTORM imaging. Sci Rep 8, 8749 (2018)<\/a><\/p>\n

M.E. Siemons, N.A.K. Hanemaaijer, M.H.P. Kole, & al; “Robust adaptive optics for localization microscopy deep in complex tissue”; Nat Commun 12, 3407 (2021).<\/a><\/p>\n

[\/et_pb_text][et_pb_button button_url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjM2MCJ9fQ==@” button_text=”Go to SMLM techniques page” button_alignment=”center” button_alignment_tablet=”center” button_alignment_phone=”center” button_alignment_last_edited=”off|desktop” disabled_on=”off|off|off” _builder_version=”4.23.1″ _dynamic_attributes=”button_url” _module_preset=”default” custom_button=”on” button_text_size=”16px” button_text_color=”#000000″ button_bg_color=”#0cb8dc” button_border_width=”0px” button_border_color=”#50D3E1″ button_border_radius=”100px” button_font=”Montserrat|600|||||||” button_icon=”$||divi||400″ global_colors_info=”{}”][\/et_pb_button][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ disabled_on=”off|off|off” _builder_version=”4.23.1″ _module_preset=”default” background_color=”#cbe9fb” bottom_divider_style=”wave” bottom_divider_color=”#0e0a0f” bottom_divider_height=”70px” global_colors_info=”{}”][et_pb_row use_custom_gutter=”on” gutter_width=”2″ _builder_version=”4.23.1″ _module_preset=”default” max_width=”1400px” custom_margin=”||35px||false|false” custom_padding=”0px||0px||true|false” custom_css_main_element=”display: flex;” global_colors_info=”{}” custom_css_main_element_last_edited=”on|phone” custom_css_main_element_phone=”display: block;” custom_css_main_element_tablet=”display: flex;”][et_pb_column type=”4_4″ _builder_version=”4.20.1″ _module_preset=”default” custom_css_main_element=”margin: auto;” global_colors_info=”{}”][et_pb_heading title=”Webinars & videos” _builder_version=”4.23.1″ _module_preset=”default” title_level=”h2″ title_font=”Montserrat|700|||||||” title_text_color=”#000000″ title_font_size=”25px” custom_margin=”||0px||false|false” locked=”off” global_colors_info=”{}”][\/et_pb_heading][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_2,1_2″ use_custom_gutter=”on” gutter_width=”2″ make_equal=”on” _builder_version=”4.23.1″ _module_preset=”default” max_width=”1400px” custom_padding=”0px||0px||true|false” custom_css_main_element=”display: flex;” global_colors_info=”{}” custom_css_main_element_last_edited=”on|phone” custom_css_main_element_phone=”display: block;” custom_css_main_element_tablet=”display: block;”][et_pb_column type=”1_2″ _builder_version=”4.20.1″ _module_preset=”default” global_colors_info=”{}”][et_pb_video src=”https:\/\/www.youtube.com\/watch?v=zPZpm1r7bTc&ab_channel=ImagineOptic” image_src=”\/\/i.ytimg.com\/vi\/zPZpm1r7bTc\/hqdefault.jpg” use_icon_font_size=”on” icon_font_size=”70px” _builder_version=”4.23.1″ _module_preset=”default” max_width=”80%” max_width_tablet=”100%” max_width_phone=”100%” max_width_last_edited=”on|tablet” module_alignment=”center” box_shadow_style=”preset1″ global_colors_info=”{}”][\/et_pb_video][et_pb_text _builder_version=”4.23.1″ _module_preset=”default” text_font=”Montserrat||||||||” text_text_color=”#000000″ text_font_size=”13px” text_orientation=”center” global_colors_info=”{}”]<\/p>\n

WEBINAR \u2013 PSF Optimization for 3D Super Resolution Microscopy<\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.20.1″ _module_preset=”default” custom_css_main_element=”margin: auto;” global_colors_info=”{}”][et_pb_video src=”https:\/\/www.youtube.com\/watch?v=OJ_3IDQcriY” image_src=”\/\/i.ytimg.com\/vi\/OJ_3IDQcriY\/hqdefault.jpg” use_icon_font_size=”on” icon_font_size=”70px” _builder_version=”4.23.1″ _module_preset=”default” max_width=”80%” max_width_tablet=”100%” max_width_phone=”100%” max_width_last_edited=”on|tablet” module_alignment=”center” box_shadow_style=”preset1″ global_colors_info=”{}”][\/et_pb_video][et_pb_text _builder_version=”4.23.1″ _module_preset=”default” text_font=”Montserrat||||||||” text_text_color=”#000000″ text_font_size=”13px” text_orientation=”center” global_colors_info=”{}”]<\/p>\n

WEBINAR \u2013 Adaptive Optics in SMLM for deep tissue imaging<\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row use_custom_gutter=”on” gutter_width=”2″ _builder_version=”4.20.1″ _module_preset=”default” max_width=”1400px” custom_padding=”||0px||false|false” custom_css_main_element=”display: flex;” global_colors_info=”{}” custom_css_main_element_last_edited=”on|phone” custom_css_main_element_phone=”display: block;” custom_css_main_element_tablet=”display: flex;”][et_pb_column type=”4_4″ _builder_version=”4.20.1″ _module_preset=”default” custom_css_main_element=”margin: auto;” global_colors_info=”{}”][et_pb_button button_url=”https:\/\/www.youtube.com\/@imagineoptic5430\/videos” url_new_window=”on” button_text=”See more videos” button_alignment=”center” button_alignment_tablet=”center” button_alignment_last_edited=”off|desktop” disabled_on=”off|off|off” _builder_version=”4.23.1″ _module_preset=”default” custom_button=”on” button_text_size=”16px” button_text_color=”#000000″ button_bg_color=”#0cb8dc” button_border_width=”0px” button_border_color=”#50D3E1″ button_border_radius=”100px” button_font=”Montserrat|600|||||||” button_icon=”||divi||400″ custom_margin_tablet=”||20px||false|false” custom_margin_phone=”||25px||false|false” custom_margin_last_edited=”on|desktop” global_colors_info=”{}”][\/et_pb_button][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"

MicAO, an adaptive optics modulefor super resolution microscopyby correcting aberrationsand go 3Dup to 50\u00b5m depthMicAO Adaptive Optics (AO) device is the first AO add-on module dedicated to techniques such as PhotoActivation Localization Microscopy (PALM), Stochastic Optical Reconstruction Microscopy (STORM) and Single Particle Tracking (SPT). This module will enable you to get a better resolution in […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":176,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"dipi_cpt_category":[],"class_list":["post-28","page","type-page","status-publish","hentry"],"yoast_head":"\nAdaptive optics module | SMLM | MicAO<\/title>\n<meta name=\"description\" content=\"Learn more about MicAO, an adaptive optics module dedicated to SMLM techniques (PALM, STORM, SPT...). 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