Multiphoton Microscopy
Correct
aberrations
Boost
fluorescence
Image
deeper
About the technique
Multiphoton microscopy is usually used to image very deep inside the biological sample.
Typically these are optically inhomogenious because of a number of refractive index variations which are causing aberrations.
This affects the quality of the PSF, which eventually degrades image quality.
What can AO bring ?
Implement on excitation pathway
and boost significantly the fluorescence signal from your biological sample
Correct the system and sample-induced aberrations
with a typical gain of 3 to 5 times the two-photon effect
Increase fluorescence signal
and either reach deeper layers of your sample or decrease excitation laser intensity to minimize photo-toxicity
Related products
Applications examples
Application & Technical notes coming soon